Dermamelan® is a patented method for treating hyperpigmentation by reducing melanin overproduction and limiting the formation of new pigment spots in the long term. This method is based on scientific and clinical studies in collaboration with leading dermatology clinics and doctors, as explained by Anita Puļķe, a cosmetologist at the "Health Center 4" branch "Anti-Aging Institute."

Dermamelan® is a specific, intensive therapeutic method developed for treating and controlling the most complicated forms of hyperpigmentation, and it is supervised exclusively by specialists.

This procedure not only aims to prevent hyperpigmentation but also corrects it at the cellular level by inhibiting or slowing down the production of melanin itself. The corrective action of Dermamelan® is specifically targeted at melanocyte cells, slowing down melanin synthesis, inhibiting the transfer of melanin from melanocytes to keratinocytes, reducing the activity of enzymes that stimulate melanin synthesis, and decreasing inflammation and vascular reactions involved in the development of hyperpigmentation.

The Dermamelan® procedure is also effective in cases where undesirable pigmentation has occurred after skin inflammation processes, such as acne, pimples, etc., as well as after injuries.

Indications for Dermamelan® include:

• All types of hyperpigmentation,
• Hormone-dependent pigmentation (following pregnancy, during the use of oral contraceptives, hormonal changes associated with aging, menopause).

Procedure Process: The Dermamelan® treatment course lasts four months, during which the client uses home skin care products. In the first consultation, the specialist conducts a thorough collection of anamnesis, examines the skin, and prepares it for the procedures. If there are contraindications, these are communicated to the client, along with all nuances that must be observed during the treatment course.

Afterward, the client receives three Dermamelan® products for home skin care, to be used for four months:

• A product for hyperpigmentation treatment (containing specific patented active substances, retinol, acids, etc.),
• A medicinal moisturizing product to prevent side effects and complications that may individually occur depending on the skin condition and type (redness, skin flaking, tight sensation, etc.),
• A product with sun protection factor SPF 130.

The specialist explains how to use the products, in what order, what to consider, and what changes to make during therapy. To provide answers to all questions arising during the treatment process, the specialist is available for communication with the client throughout the four months.

Contraindications: Dermamelan® is not recommended in the following cases:

• During pregnancy and breastfeeding,
• If there is an allergy to any of the product ingredients,
• Use of photosensitive medications, such as Isotretinoin (therapy can begin after the use of these medications),
• Patients with acute bacterial, viral, fungal, or herpes infections in the treatment area,
• Patients with very thin, dehydrated, or desiccated skin (after treating this problem, the specialist will offer a modified or adapted treatment to reduce hyperpigmentation),
• During aesthetic medical procedures (laser, mesotherapy, etc.).

Dermamelan® - Two in One: The Dermamelan® treatment course not only provides effective hyperpigmentation treatment but also has an intense anti-aging effect, significantly improving skin quality and condition – making it smooth, radiant, and toned.

Effectiveness of Combined Procedures: Dermamelan® procedures are also recommended to be combined with laser therapy for reducing hyperpigmentation. This is one of the most popular procedures worldwide and, taking into account each client's individual skin properties (sensitivity, skin structure, phototype, etc.), is successfully applied by specialists at the "Health Center 4".

Price for the Four-Month Course of Dermamelan® Procedures: 800-850 EUR.

Additionally, there are procedures with Cosmelan®, which have a different concentration of active ingredients (the course takes six months).

Information: The medicinal cosmetics manufacturer "Mesoestetic" (Spain) has developed an innovative formula for Cosmelan® and Dermamelan® methods, based on scientific research, its long experience in this field, and the latest possibilities offered by artificial intelligence in data and information processing. In developing these methods, "Mesoestetic" has introduced two new patents, Melaphenone and [SYN]pigment target, which allow regulating and correcting the appearance and recurrence of pigmentation in the long term.

About Pigmentation: Melanin, the pigment that colors our skin and forms pigmented spots on our skin, is produced by melanocyte cells. If their activity is activated by hormones and other aggressive conditions, the cells start to produce this pigment uncontrollably and excessively. This leads to the formation of melanin accumulations in various places, developing hyperpigmentation.

Pigmentation disorders are usually associated with intracellular processes (developing in melanocytes) and extracellular processes (related to surrounding cells – keratinocytes, which also ensure the transport of the melanin pigment), therefore, treatment requires a complex approach.

Moreover, the hyperpigmentation process is also associated with inflammation and vascular reactions, making treatment complicated. As mentioned, it is related to the hormonal background. To prevent and treat hyperpigmentation (epidermal, dermal, and combined) comprehensively, "Mesoestetic" has created the Cosmelan® and Dermamelan® methods. These are in-depth, intensive, specific depigmenting treatments under specialist supervision.

These procedures serve not only for the medicinal prevention of hyperpigmentation but also correct it at the cellular level. Thus, hyperpigmentation is treated comprehensively – controlling various mechanisms of pigmentation, reducing melanin synthesis without destroying the cell functions themselves.

Cosmelan® and Dermamelan® procedures are also effective in cases where undesirable pigmentation has arisen after skin inflammation processes, such as acne, pimples, and other inflammatory processes.