transepidermal solutions by mesoestetic® is the widest range of solutions for transepidermal application for performing combinable, safe, effective cosmetic treatments. Formulations with specific, selected active ingredients for the purpose of treating all types of aesthetic facial, body and hair concerns.

Collapsible content

Versatile non-invasive professional treatments

It is the most complete range of solutions and specific active ingredients in sterile ampoules for transcutaneous application. offers the professional the possibility to select specific active ingredients or ready made-cocktails to design bespoke facial, body and hair treatments.

The range has 2 lines:


The line has 10 cocktails of active ingredients to treat aging, skin spots, cellulitis, facial and body flaccidity as well as fluid retention. The cocktails’ highly concentrated formulations, have been designed to guarantee a therapeutic response of the highest order. The cocktails’ wide range of active ingredients promote the natural processes of cellular repair, as well as alleviating the alterations to the skin tissue. Its pH is within the range of physiological pH, between 6.5 and 7.5, thus ensuring maximum skin tolerance.


After making a diagnosis to establish the requirements of their patient, the professional can choose from the 24 active ingredients that comprise the line and apply them either individually or combined as cocktails.

What is transcutaneous application?

This is a minimally-invasive technique that permits the penetration of active ingredients in the epidermis and dermis where they have maximum efficiency without the need for needles. The treatments are performed with dermaroller (microneedling technique) or with equipment (electroporation, ionophoresis, ultrasound, IR thermotherapy).

Also known as collagen induction therapy. It is performed using a dermaroller, a roller that has a multitude of micro-needles on its head.

When passed over the area to be treated it opens micro-canals in the epidermis, facilitating the penetration of the simultaneously-applied active ingredients into the skin. The microscopic punctures made by the roller stimulate the skin’s healing and repair mechanisms, achieving a natural production of collagen and elastin.

Diagnosis, protocol and maintenance


1. Cleanse the area to be treated with hydramilk and hydratonic

2. Select the solution suited to the requirements of the skin. Depending on the patient’s sensitivity cold is locally applied to minimize the feeling of discomfort, under no circumstance is anesthetic cream to be used.

3. Roll the dermaroller and simultaneously apply the solution over the area being treated.

4. Massage the area.

5. Apply a high-protection sunscreen. The application of a SPF50+ sunscreen three times a day is recommended throughout the treatment period


1. Preparation of the skin

Degrease the skin of the area to be treated with a gauze soaked with professional degreasing lotion.

2. Preparing the session and application protocol

Select the solution suited to the needs of the area being treated and mix with mesogel base, shaking the contents until it is completely dissolved. Fit the bottle of mesogel base to the roll-on of the equipment.

Commence the treatment sliding the roll-on over the area to be treated, making slow movements without excessive pressure, allowing a progressive absorption of the active ingredients.

Occasional application to the most affected areas.


Remove the remaining mesogel and apply the finishing product adapted to the treatment performed.

Finish with the application of moisturizing sun protection.

4. Home treatment

Select the home treatment that best suits the patient’s needs.


all products