Its unique and innovative formula safely and efficiently removes existing spots and prevents.
-
specialists in depigmentation
At mesoestetic®, we are depigmentation experts. More than 30 years of research in this field and the experience of thousands of patients around the world make us the reference company.
-
innovation endorsed by two patents
Our knowledge and the use new technologies in this development has led us to submitting two new patents that endorse the uniqueness of dermamelan®.
-
excellent clinical results
Tested on all types of spots, dermamelan® has shown high efficacy and safety in all types of skin spots.
-
high satisfaction from the patient
A progressive treatment that provides visible results from the first weeks and maintains the skin's uniformity and quality in the long term.

What is the dermamelan® method and how does it work?
dermamelan® is the medical depigmenting method that efficiently and progressively eliminates spots by acting on the accumulation of pigment in the skin and on the root of the problem, providing a comprehensive and long-lasting outcome.
The treatment consists in a first session in consultation and a home treatment that lasts 4 months.

Would you like to find out more about skin spots?
Skin spots are a very common problem, especially in women. It involves the darkening of the skin caused by an overproduction of pigment or melanin that unevenly accumulates in the skin. This overproduction is caused by an alteration of certain cellular mechanisms that lead to an excess of pigment.
There are different types of spots based on their origin and their distribution on the skin. It can appear due to several triggering factors, the most important being the result of solar radiation without protection. Other factors are also involved, such as a genetic predisposition, inflammatory conditions, hormonal changes and some photosensitising drugs (oral contraceptives, anti-inflammatory drugs, antibiotics, etc.).
It is a complex problem, and in many cases they are resistant to many medical-aesthetic treatments. In order to achieve an effective and long-lasting outcome and prevent a rebound, we must not only work on eliminating the accumulated pigment that causes the visible darkening, but also on treating the pathology's cellular origin, with the aim of stopping the overproduction of melanin and thus preventing the spots from reappearing.
all products
-
Example product title
Regular price €19,99 EURRegular priceUnit price per -
Example product title
Regular price €19,99 EURRegular priceUnit price per -
Example product title
Regular price €19,99 EURRegular priceUnit price per -
Example product title
Regular price €19,99 EURRegular priceUnit price per
FAQs dermamelan®
How do I know if this treatment is for me?
Suitability of the use ofdermamelan®for you can be discussed with your chosen medical specialist during your consultation.
Is it a completely painless treatment?
It is a process in which the skin is completely renewed gradually and on a controlled basis. During the initial phase and after treatment at the clinic, the skin appears reddened and you can feel warmth, but these are mild, expected reactions that will disappear after 24-48 hours. During the home phase, it is normal to experience a slight flaking and sometimes some sensitivity can be felt. These effects disappear with the application of the home products recommended by your specialist.
Is it a treatment compatible with my daily activities?
dermamelan®is a non-invasive topical treatment and does not prevent you following a normal life. It is however vitally important that the daily homecare regime is maintained and sun exposure Will need to be avoided as far as possible.
Will spots disappear completely and forever?
Spots will be very significantly reduced following the treatment however where there has been a spot there will always be a trend for reappearance. It is essential to follow your homecare routine and to constantly use specific photoprotection that prevents repigmentation. Your skin specialist will be able to advise you on the best products for you.
What is the best time of year to perform the treatment?
If you do not follow the home regimen, you are interrupting the treatment and will therefore not obtain the expected results. Not applying cosmelan 2 depigmenting cream with regulating action involves not regulating the melanocyte and, therefore, a persistent uncontrolled, excessive production of melanin. The spot will reappear as the skin layers are renewed, as melanin migrates to the surface making the spot increasingly evident.
Not using photoprotection, melan 130 pigment control, involves a very high risk that the spot returns, as skin is more sensitive and receptive to external aggressions during the treatment.
Can I combine the cosmelan method with other depigmentation treatments?
During at least the first three months of the method, it is not recommended to use any other type of minimally invasive treatment that can cause a skin lesion, as well as peels, microneedling, exfoliations, etc., as it can even cause repigmentation. It is advisable to use soothing and regenerating treatments both in cabin and at home in case it is needed.
In the last months where we reduce the application guidelines of cosmelan 2 only to the night, we can combine it with treatments that help prolong the results, such as melan tran3x concentrate and melan tran3x gel-cream.
Does the treatment make me unable to fulfil my daily life activities normally?
Does the treatment make me unable to fulfil my daily life activities normally?
As it is not an invasive treatment, it does not make you unable to fulfil your activities of daily living normally. Caution must be exerted when fulfilling some type of activities during the first days, a skin adaptation period after the cabin treatment. For instance, it is advisable to avoid bathing in swimming pools, prolonged sun exposure and activities that involve excessive sweating.
Can the spots return after the end of treatment?
After an adequate professional treatment, excess pigmentation can be removed visibly. However, it is a dynamic process, where the imbalance forming them can cause their recurrence. Therefore, even if the spots are not seen, it is essential to apply a daily regulatory depigmentation treatment and photoprotection throughout the year to prevent repigmentation.
How can I prevent the appearance of spots after the treatment?
In case you are under the effect of any of the triggering factors for the appearance of spots (contraceptives, pregnancy, summer season, post-depilation, post-acne, post-peel, under photosensitising treatment, etc.), a daily treatment routine is essential, combining a depigmentation treatment, such asmelan tran3x, with a high photoprotector such asmelan 130 pigment control.
Does the cosmelan® treatment have side effects?
If used correctly and under the supervision of a professional, there should be no side effects. cosmelan® is a topical treatment, therefore minimally invasive, that does not prevent you from following your normal daily life. During the initial phase and following the treatment in consultation, the skin may become irritated or show redness. This is totally normal and expected, and it will disappear within a few days. During the home phase, it is common to experience slight peeling and sensitivity, which are symptoms that disappear when applying the home products recommended by the specialist.
How does cosmelan® act against acne?
cosmelan® is a depigmentation treatment; therefore, it is not indicated to treat active acne. If you would like to treat acne in its different phases of acneic and seborrhoeic skin, we recommend the acnelan medical treatment (active link to acnelan's consumer page). However, acne has an inflammatory component that can lead to the appearance of skin spots, known as PIH (Post-inflammatory Hyperpigmentation). cosmelan® is effective on this type of spots caused by acne, in all skin types and phototypes.
What is the main difference between cosmelan® and dermamelan®?
Both are depigmentation treatments that produce excellent results, but cosmelan® is an aesthetic treatment, whereasdermamelan®is a treatment that requires a doctor's supervision and monitoring. The newdermamelan®is a new generation treatment that, thanks to the development of an unedited formula, has two patents that allow for a more comprehensive and effective action when treating the most severe and resistant spots. This innovation has led to a more efficient and convenient protocol with results after 4 months of treatment.
cosmelan® peel: is cosmelan® a peel?
Although often referred to ascosmelan® peel, thecosmelan® treatment goes beyond a peel. Unlike peels, which act on the surface of the problem, cosmelan® gets to the root of the problem. It consists in a treatment that visibly removes and attenuates pigmentation spots (like a peel) while exerting a regulating action that corrects the overproduction of pigmentation and prevents the spots from reappearing.